Author

Miguel A. Medina-Serpas

University of Florida HealthORCID 0000-0003-0532-5413Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Organism:human· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Todd M. BruskoiD· 2 shared Abdelbasset A. FarahatiD· 1 shared Ali NajiiD· 1 shared Amanda L. PosgaiiD· 1 shared Arabella YoungiD· 1 shared Asit Kumar MannaiD· 1 shared C Liu· 1 shared Dean R TantiniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Todd M. BruskoORCID

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2 papers

Recent·Most cited

ImmunologyCell ReportsPeer-reviewedMar 23, 2026

Spatial transcriptomics from pancreas and local draining lymph node tissue reveals a lymphotoxin-β signature in human type 1 diabetes

Miguel A. Medina-Serpas, Maigan Brusko, Gregory J. Golden…·Todd M. Brusko

This study uses spatial transcriptomics to identify inflammation signatures in pancreas and lymph node tissues of T1D patients, highlighting LTB and other genes involved in disease pathogenesis.

8 citationstop 1%

humanspatial transcriptomics

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ImmunologybioRxivPreprintOct 22, 2025

OCA-B/Pou2af1 Expression in T Cells Promotes PD-1 Blockade-Induced Autoimmunity but is Dispensable for Anti-Tumor Immunity

Junhong Du, Asit Kumar Manna, Miguel A. Medina-Serpas…·Dean R Tantin

This study shows OCA-B in T cells promotes ICI-induced autoimmunity but is not needed for anti-tumor immunity, suggesting it could be targeted to prevent autoimmunity without harming cancer treatments.

DOI 10.1101/2025.10.22.683978

mousebulk RNA-seq

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