Author

Keith Coughlan

Munster Technological UniversityORCID 0000-0003-0547-7919Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Research Focus:benchmarking· 1 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Francesca BottaciniiD· 2 shared Andrew L. LoveringiD· 1 shared Bruno Gabriel Nascimento AndradeiD· 1 shared Cassie R. BakshaniiD· 1 shared Douwe van SindereniD· 1 shared Haithem AfliiD· 1 shared Jamie A. FitzGeraldiD· 1 shared Lucy I. CrouchiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

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10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

Francesca BottaciniORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintJul 17, 2025

PNGaseA-mediated N-glycan stripping from peptides by infant-derived Bifidobacterium bifidum

Cassie R. Bakshani, Taiwo O. Ojuri, Simon G. Caulton…·Lucy I. Crouch

This paper characterizes a PNGaseA enzyme from Bifidobacterium bifidum that preferentially strips N-glycans from peptides over proteins, revealing its structural basis for substrate specificity.

DOI 10.1101/2025.07.17.665090

bacteria (other)proteomics

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BioinformaticsbioRxivPreprintJun 27, 2025

Alignment-free Bacterial Taxonomy Classification with Genomic Language Models

Mike Leske, Jamie A. FitzGerald, Keith Coughlan…·Bruno Gabriel Nascimento Andrade

This paper evaluates genomic language models for bacterial classification using 16S rRNA sequences, showing they match or outperform BLAST+ and VSEARCH in species-level classification.

1 citation

bacteria (other)DNA methylation

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