Douwe van Sinderen

This study identifies raffinose as a dietary fiber that promotes bifidobacterial persistence in the gut during weaning, with implications for host health and inflammation.

The paper identifies a novel gene cluster in Bifidobacterium pseudolongum that enables resistant starch utilization, linking CAZyme profiles to niche adaptation in infant and adult microbiomes.

This paper characterizes a PNGaseA enzyme from Bifidobacterium bifidum that preferentially strips N-glycans from peptides over proteins, revealing its structural basis for substrate specificity.

The paper identifies a novel subspecies of Bifidobacterium longum, BL. nexti, in infant gut microbiomes, showing its association with formula feeding and vertical transmission.

This study shows that maternal colonization with Bifidobacterium breve during pregnancy alters fetal brain metabolism and expression of key pathways.

FANGORN provides a quality-checked database of full-length 16S-ITS-23S rRNA operons to improve microbial community classification and phylogenetic analysis.

This study develops an endogenous CRISPR-Cas system for gene editing in Bifidobacterium breve, enabling deletion, substitution, and continuous editing of target genes.