Author

Bálint Dér

Semmelweis UniversityORCID 0000-0003-0604-8411Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Assay:CRISPR screen· 1

Frequent Co-Authors

Andrew P. McMahoniD· 3 shared Helena BugacoviD· 2 shared Nils O. LindströmiD· 2 shared Ariel C. VonkiD· 1 shared Biao HuangiD· 1 shared Bohdana-Myroslava Briantseva· 1 shared Brendan H. GrubbsiD· 1 shared Chennan C. Zhang· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersDevelopmental Biology

Andrew P. McMahonORCID

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3 papers

Recent·Most cited

Developmental BiologyDevelopmentPeer-reviewedSep 15, 2024

Cadherin Adhesion Complexes Direct Cell Aggregation in the Epithelial Transition of Wnt-Induced Nephron Progenitor Cells

Bálint Dér, Helena Bugacov, Bohdana-Myroslava Briantseva, Andrew P. McMahon

This study shows that Wnt-{beta}-catenin pathway activates cadherin-mediated cell adhesion, driving cell aggregation during the mesenchymal-to-epithelial transition of nephron progenitor cells.

18 citations

mouseexperimental assay

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Developmental BiologybioRxivPreprintAug 20, 2023

Canonical Wnt transcriptional complexes are essential for induction of nephrogenesis but not maintenance or proliferation of nephron progenitors

Helena Bugacov, Bálint Dér, Sunghyun Kim…·Andrew P. McMahon

The paper investigates the role of canonical Wnt transcriptional complexes in nephron progenitor cell regulation, finding distinct roles in induction versus maintenance of nephrogenesis.

2 citations

mousebulk RNA-seq

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Developmental BiologybioRxivPreprintMay 25, 2023

Modeling kidney development, disease, and plasticity with clonal expandable nephron progenitor cells and nephron organoids

Biao Huang, Zipeng Zeng, Hui Li…·Zhongwei Li

This paper develops a synthetic niche to expand nephron progenitor cells, enabling organoid generation and CRISPR screening for kidney development and disease.

2 citations

humanmouse

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