ImmunologybioRxivPreprint
Endothelial PTBP1 Deletion in Transplanted Cardiac Tissue Limits Cardiac Allograft Vasculopathy
Christopher L. Pathoulas, Koki Hayashi, Ivy A. Rosales…·Patrick A. Murphy
This study identifies PTBP1 as a key regulator of endothelial dysfunction in cardiac allograft vasculopathy, showing its deletion reduces fibrosis and immune activation in mouse models.