Trent M. Prall

The paper develops EpiSignaLR, a resource for genome-wide episignature analysis using methylation-aware sequencing data, identifying DMRs and classifiers for three neurodevelopmental disorders.

Mahi-mahi accurately genotypes repeat expansions from nanopore sequencing data, matching orthogonal methods and identifying pathogenic alleles.

This paper evaluates long-read sequencing with targeted assembly for accurately analyzing the opsin gene cluster, showing high concordance and improved detection of color vision deficiencies and carrier status.

This study evaluates factors affecting haplotype phasing accuracy in long-read sequencing, showing that T2T reference genomes and longer reads improve performance.

This paper introduces an integrated microfluidic workflow for Oxford Nanopore sequencing that reduces hands-on time and sample loss while enabling high-quality library preparation from small sample volumes.

The paper reports the assembly of multiple IGH haplotypes from Mauritian cynomolgus macaques using long-read sequencing, revealing genetic diversity and novel alleles not previously cataloged.

The paper assembles KIR and NKG2 genomic haplotypes in Mauritian cynomolgus macaques using long-read sequencing and develops a strategy for genotyping using short-read data.

The paper fully assembles and annotates a cynomolgus macaque MHC haplotype using long-read sequencing, revealing structural diversity and gene counts different from previous rhesus macaque haplotypes.

The paper presents an improved chromosome-scale genome assembly for the Syrian hamster using long-read sequencing, resulting in higher continuity and gene annotation accuracy.

SNAILS improves long-read sequencing by automating slow pipetting, increasing read length and consistency in Oxford Nanopore library preparation.

The paper characterizes 100 extended MHC haplotypes in Indonesian cynomolgus macaques using sequencing and haplotype analysis to improve preclinical research applications.

The paper improves KIR allele discovery in Mauritian cynomolgus macaques using high-throughput sequencing and develops a new target capture reagent, finding nine novel alleles.