Ronald Alan Harris

Low mutation rate but high male-bias in the germline of a short-lived opossum

This study reports the lowest germline mutation rate in mammals and a typical male mutation bias in the gray short-tailed opossum, suggesting alternative mechanisms to cell division drive sex-specific mutation rates.

Unprecedented female mutation bias in aye-ayes

This study finds a female mutation bias in aye-ayes, contrasting the typical male mutation bias in mammals, and identifies potential genetic causes.

Complete genomic assembly of Mauritian cynomolgus macaque killer immunoglobulin-like receptor and natural killer group 2 haplotypes

The paper assembles KIR and NKG2 genomic haplotypes in Mauritian cynomolgus macaques using long-read sequencing and develops a strategy for genotyping using short-read data.

The landscape of tolerated genetic variation in humans and primates

The paper uses primate genetic data to predict human variant pathogenicity with a deep learning classifier trained on 4.3 million common missense variants.

A global catalog of whole-genome diversity from 233 primate species

This study presents whole-genome data from 233 primate species, revealing patterns of genetic diversity, mutation rates, and recurrent missense mutations across primate clades.

Loci on chromosome 12q13.2 encompassing ERBB3, PA2G4 and RAB5B are associated with polycystic ovary syndrome

The paper identifies 15 SNPs associated with androgen production in theca cells and a haplotype on chromosome 12q13.2 linked to PCOS and AMH levels.

Construction of a new chromosome-scale, long-read reference genome assembly for the Syrian hamster, Mesocricetus auratus

The paper presents an improved chromosome-scale genome assembly for the Syrian hamster using long-read sequencing, resulting in higher continuity and gene annotation accuracy.

Infant Inhibited Temperament in Primates Predicts Adult Behavior, is Heritable, and is Associated with Anxiety Relevant Genetic Variation

The paper shows infant inhibited temperament in monkeys predicts adult behavior, is heritable, and links to anxiety-related genetic variants.

SVhound: Detection of future Structural Variation hotspots

SVhound predicts regions likely to contain novel structural variations by analyzing population-level SV datasets, showing high correlation with full datasets and applicability across species.

Variation in predicted COVID-19 risk among lemurs and lorises

The paper analyzes ACE2 gene sequences in strepsirrhine primates to assess their susceptibility to SARS-CoV-2, finding high variability and potential risk in some species.

Improved full-length killer cell immunoglobulin-like receptor transcript discovery in Mauritian cynomolgus macaques

The paper improves KIR allele discovery in Mauritian cynomolgus macaques using high-throughput sequencing and develops a new target capture reagent, finding nine novel alleles.