Author

Owen M. Wolkowitz

University of California, San FranciscoORCID 0000-0003-0655-5042Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Physiology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1

Frequent Co-Authors

Synthia H. MelloniD· 3 shared Victor I. ReusiD· 2 shared Aarti GautamiD· 1 shared Alexandra Morford· 1 shared Bernie J. DaigleiD· 1 shared Charles R. MarmariD· 1 shared Christina M. Hough· 1 shared Colm G. ConnollyiD· 1 shared

Activity by Year

2018-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersNeuroscience

Synthia H. MellonORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintJan 11, 2025

Kynurenine Metabolism is Associated with Antidepressant Response to Selective Serotonin Reuptake Inhibitors

Ryan Rampersaud, Klara Suneson, Gwyneth W. Y. Wu…·Lena Brundin

This study examines how changes in kynurenine pathway metabolite ratios relate to antidepressant response in patients treated with SSRIs, finding specific shifts in neuroprotective-to-neurotoxic metabolite balances.

3 citations

humanstatistical model

𝕏 PostBluesky

Systems BiologybioRxivPreprintDec 17, 2018

Mechanistic insights on metabolic dysfunction in PTSD: Role of glucocorticoid receptor sensitivity and energy deficit

Pramod Rajaram Somvanshi, Synthia H. Mellon, Janine Dyck Flory…·Ruoting Yang

The paper uses a systems biology approach to analyze how glucocorticoid receptor sensitivity and energy deficit contribute to metabolic dysfunction in PTSD.

4 citations

humanmetabolomics

𝕏 PostBluesky

PhysiologybioRxivPreprintOct 22, 2018

Cortisol Predicts Antidepressant Treatment Outcome, Memory Improvement, and Brain Response to Negative Emotions: The Importance of Aging

Felipe A. Jain, Colm G. Connolly, Victor I. Reus…·Owen M. Wolkowitz

This study shows that age moderates how cortisol levels relate to depression diagnosis, treatment response, and brain activity to negative emotions.

DOI 10.1101/450213

humanstatistical model

𝕏 PostBluesky