Systems BiologyCell SystemsPeer-reviewed
Circuit to target approach defines an autocrine myofibroblast loop that drives cardiac fibrosis
Shoval Miyara, Miri Adler, Kfir Baruch Umansky…·Eldad Tzahor
The paper models a macrophage-myofibroblast circuit to predict fibrosis types and shows targeting the myofibroblast autocrine loop reduces fibrosis after myocardial infarction.
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