Author

Shoval Miyara

Weizmann Institute of ScienceORCID 0000-0002-9003-046XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 3 Systems Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Uri AloniD· 4 shared Avi MayoiD· 3 shared David L. GibbsiD· 2 shared Deng Pan· 2 shared Eldad TzahoriD· 2 shared Eviatar WeizmaniD· 2 shared Isaac Shalom· 2 shared Jacob ElkahaliD· 2 shared

Activity by Year

2025-2025 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersCancer Biology

Uri AlonORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

OSDR2.0 infers microenvironment-driven cell-state transitions and population dynamics from a single spatial biopsy

Isaac Shalom, Jonathan Somer, Shoval Miyara, Avi Mayo, Shie Mannor, Uri Alon

OSDR2.0 infers cell-state transitions and population dynamics from spatial biopsies, improving treatment response prediction in TNBC.

bioRxiv · Sep 2, 2025 · PreprintCancer Biology

A fibroblast-centric network drives cold fibrosis in the tumor microenvironment of lung squamous cell carcinoma

Shoval Miyara, Shachaf Frenkel, Avi Mayo, Philippe D. Gascard, Michael Strasser, David L. Gibbs, Eviatar Weizman, Isaac Shalom, Yaniv Stein, Deng Pan, Joseph A. Caruso, Veena Sangwan, Nicholas Bertos, Julie Bérubé, Sophie Camilleri‐Broët, , Uri Alon

The paper identifies a cold fibrotic network in LUSC TME driven by CAFs and shows its conservation in other CIACs, suggesting therapeutic targets.

bioRxiv · Aug 25, 2025 · PreprintCancer Biology

A Fibroblast State Choreographs an Epithelial YAP-dependent Regenerative Program Essential to (Pre)malignancy via ECM-mediated Mechanotransduction

Deng Pan, Philippe D. Gascard, Joseph A. Caruso, Chira Chen‐Tanyolac, Veena Sangwan, Nicholas Bertos, Sophie Camilleri‐Broët, Julie Bérubé, Spyridon Oikonomopoulos, Michael K. Strasser, David L. Gibbs, Joanna Bons, Jordan B. Burton, Jacob Rose, Samah Shah, , Thea Dorothy Tlsty

The paper identifies a fibroblast state called STIF that drives YAP-dependent regenerative programs and (pre)malignancy through mechanotransduction in response to tissue injury.

bioRxiv · Jul 11, 2025 · PreprintCancer Biology

Circuit to target approach defines an autocrine myofibroblast loop that drives cardiac fibrosis

Shoval Miyara, Miri Adler, Kfir Baruch Umansky, Daniel Häußler, Elad Bassat, Yalin Divinsky, Jacob Elkahal, David Kain, Daria Lendengolts, Ricardo O. Ramirez Flores, Hanna Bueno-Levy, Ofra Golani, Tali Shalit, Michael Gershovits, Eviatar Weizman, , Eldad Tzahor

The paper models a macrophage-myofibroblast circuit to predict fibrosis types and shows targeting the myofibroblast autocrine loop reduces fibrosis after myocardial infarction.

Cell Systems · Feb 18, 2025Peer-reviewedSystems Biology