Author

Alexander Genzelinakh

Weizmann Institute of Science

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Avraham ShakkediD· 2 shared Daria Lendengolts· 2 shared David KainiD· 2 shared Eldad TzahoriD· 2 shared Kfir Baruch UmanskyiD· 2 shared Achim KrügeriD· 1 shared Alessandra MorettiiD· 1 shared Alla AharonoviD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersSystems Biology

Avraham ShakkedORCID

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2 papers

Recent·Most cited

Circuit to target approach defines an autocrine myofibroblast loop that drives cardiac fibrosis

Shoval Miyara, Miri Adler, Kfir Baruch Umansky, Daniel Häußler, Elad Bassat, Yalin Divinsky, Jacob Elkahal, David Kain, Daria Lendengolts, Ricardo O. Ramirez Flores, Hanna Bueno-Levy, Ofra Golani, Tali Shalit, Michael Gershovits, Eviatar Weizman, , Eldad Tzahor

The paper models a macrophage-myofibroblast circuit to predict fibrosis types and shows targeting the myofibroblast autocrine loop reduces fibrosis after myocardial infarction.

Cell Systems · Feb 18, 2025Peer-reviewedSystems Biology

ERBB2 drives YAP activation and EMT-like processes during cardiac regeneration

Alla Aharonov, Avraham Shakked, Kfir Baruch Umansky, Alon Savidor, Alexander Genzelinakh, David Kain, Daria Lendengolts, Or‐Yam Revach, Yuka Morikawa, Jixin Dong, Yishai Levin, Benjamin Geiger, James F. Martin, Eldad Tzahor

This study shows that ERBB2 activates YAP signaling through phosphorylation, driving EMT-like processes and cardiac regeneration in mice after injury.

Nature Cell Biology · Oct 12, 2020Peer-reviewedMolecular Biology