Kai Kaila

This study identifies functional GABAergic neuron-to-glioma synapses in diffuse midline gliomas that promote tumor proliferation and shows that drugs modulating GABAergic signaling affect glioma growth.

This study shows that microglial NKCC1 regulates ion homeostasis, inflammation, and brain injury through cell-autonomous mechanisms.

This paper introduces a rat model of birth asphyxia where seizures occur after, not during, hypoxia, and shows that intermittent hypoxia promotes neuronal hyperexcitability leading to seizures.

The paper investigates brain pH and PO2 changes in a rodent asphyxia model, finding that hypercapnia restores brain PO2 and protects against acidosis, unlike hypoxia.

This study investigates how splice isoforms of collybistin (CB1 and CB2) regulate neuronal maturation and synapse formation through their effects on Cdc42 and GABAAR signaling in the developing brain.