Distinct roles of the two BRCA2 DNA binding domains in DNA damage repair and replication fork preservation
Francisco E. Neal, Wenjing Li, Mollie E. Uhrig, Jeffrey N. Katz, Shahrez Syed, Neelam Sharma, Arijit Dutta, Sandeep Burma, Robert Hromas, Alexander V. Mazin, Eloise V. Dray, David S. Libich, Shaun K. Olsen, Elizabeth V. Wasmuth, Weixing Zhao, , Patrick Sung
This study identifies distinct roles of BRCA2's two DNA binding domains in DNA repair and replication fork stability using genetic and biochemical methods.
Cell Reports · May 1, 2025Peer-reviewedBiochemistry