Author

Mollie E. Uhrig

Colorado State UniversityORCID 0000-0002-4142-8260Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Approach:experimental assay· 3 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Claudia WieseiD· 3 shared Alexander V. MaziniD· 2 shared Patrick SungiD· 2 shared Youngho KwoniD· 2 shared Arijit DuttaiD· 1 shared Claus Storgaard SørenseniD· 1 shared Courtney N. JohnsoniD· 1 shared David S. LibichiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersCell Biology

Claudia WieseORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

FBH1 and RAD54L directly interact and cooperate to drive replication fork reversal

Mollie E. Uhrig, Courtney N. Johnson, Jordi Gómez, Alexander V. Mazin, Claudia Wiese

This study identifies a direct physical and functional interaction between FBH1 and RAD54L, showing they cooperate to drive replication fork reversal.

bioRxiv · May 24, 2026 · PreprintCell Biology

Phosphoregulation of RAD51AP1 function in homology-directed repair

Neelam Sharma, Mollie E. Uhrig, Youngho Kwon, Patrick Sung, Claudia Wiese

This study shows that phosphorylation of RAD51AP1 at S277/282 regulates its function in homology-directed DNA repair, with phosphomimetic variants enhancing its activity.

Journal of Biological Chemistry · Jan 12, 2026Peer-reviewedCell Biology

Distinct roles of the two BRCA2 DNA binding domains in DNA damage repair and replication fork preservation

Francisco E. Neal, Wenjing Li, Mollie E. Uhrig, Jeffrey N. Katz, Shahrez Syed, Neelam Sharma, Arijit Dutta, Sandeep Burma, Robert Hromas, Alexander V. Mazin, Eloise V. Dray, David S. Libich, Shaun K. Olsen, Elizabeth V. Wasmuth, Weixing Zhao, , Patrick Sung

This study identifies distinct roles of BRCA2's two DNA binding domains in DNA repair and replication fork stability using genetic and biochemical methods.

Cell Reports · May 1, 2025Peer-reviewedBiochemistry