Weixing Zhao

The paper engineers chimeric proteins to replace ALS-causing FUS and TDP-43, improving neuronal health by reducing aggregation and restoring nuclear functions.

This study identifies HELZ as an RNA-DNA helicase that resolves R loops to support homologous recombination repair and genomic stability.

This study identifies DNA binding and RAD51 interaction interfaces in BRCA1's disordered region and shows their distinct roles in homologous recombination and DNA repair.

This study identifies distinct roles of BRCA2's two DNA binding domains in DNA repair and replication fork stability using genetic and biochemical methods.

The paper examines how age and parental caregiving influence social brain development and Theory of Mind in children through naturalistic fMRI studies of mother-child dyads.