Thomas D. Bannister

This paper describes a trimeric inhibitor, S22, that stabilizes the SARS-CoV-2 spike protein in a closed conformation, preventing ACE2 binding and viral entry.

This study identifies Dipyridamole as a drug that rescues mitochondrial dysfunction and neuronal death in ALS and AD iPSC-derived neurons by enhancing mitochondrial pyruvate uptake.

This paper identifies potent benzamide compounds against Zika virus by targeting NS4B, showing superior potency and novel resistance mutation patterns compared to existing treatments.