Cell BiologyLife Science AlliancePeer-reviewed
The Notch1 intracellular domain orchestrates mechanotransduction of fluid shear stress
Tania Singh, Kyle A. Jacobs, William J. Polacheck, Matthew L. Kutys
The paper identifies a flow-specific Notch1 mechanotransduction pathway involving receptor polarization, endocytosis, and proteolytic activation in response to fluid shear stress.
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