Author

Michael Frech

Friedrich-Alexander-Universität Erlangen-NürnbergORCID 0000-0003-0717-3687Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Assay:imaging· 1 Assay:metagenomics· 1

Frequent Co-Authors

Eva SchmidiD· 2 shared Georg Andreas SchettiD· 2 shared Heike Danzer· 2 shared Kerstin Sarter· 2 shared Mario M. ZaissiD· 2 shared Aiden HaghikiaiD· 1 shared Alf KastbomiD· 1 shared Anna SvärdiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersImmunology

Eva SchmidORCID

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2 papers

Recent·Most cited

ImmunologyFrontiers in MicrobiologyPeer-reviewedMay 20, 2026

Microbiota-specific serum IgG links gut and joints through immune-endothelial crosstalk in arthritis

Eva Schmid, Nadine Otterbein, Stephen Ariyeloye…·Mario M. Zaiss

This study identifies microbiota-specific serum IgG as a mediator of gut-joint immune-endothelial crosstalk in arthritis, showing its role in initiating autoimmunity through endothelial barrier impairment and microbial translocation.

1 citation

mousehuman

𝕏 PostBluesky

ImmunologyJournal of Clinical InvestigationPeer-reviewedJul 10, 2025

Gut-specific H3R signaling orchestrates microglia-dependent resolution of peripheral inflammation

Kerstin Dürholz, Leona Ehnes, Mathias Linnerbauer…·Mario M. Zaiss

The paper identifies gut microbiota-derived histamine as a factor enabling the CNS to suppress peripheral inflammation in RA by activating H3R in the intestine and modulating microglia.

12 citations

mousehuman

𝕏 PostBluesky