Mario M. Zaiss

This study identifies microbiota-specific serum IgG as a mediator of gut-joint immune-endothelial crosstalk in arthritis, showing its role in initiating autoimmunity through endothelial barrier impairment and microbial translocation.

This study shows that Prevotella intestinalis induces arthritis in resistant mice by activating intestinal immune cells and promoting Th17 differentiation through IL-6.

The paper identifies gut microbiota-derived histamine as a factor enabling the CNS to suppress peripheral inflammation in RA by activating H3R in the intestine and modulating microglia.