Author

Stefan Hoppler

University of AberdeenORCID 0000-0003-0730-4798Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 3 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Marika SalonnaiD· 2 shared Andreia Sofia BernardoiD· 1 shared Anna K. BassiliD· 1 shared Boni Anatole AfoudaiD· 1 shared Claudiu Giuraniuc· 1 shared Connor Ross· 1 shared D Konstantopoulos· 1 shared David E. K. FerrieriD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersEvolutionary Biology

Marika SalonnaORCID

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4 papers

Recent·Most cited

Evolutionary BiologyBMC BiologyPeer-reviewedJan 24, 2026

Long-Read Sequencing Reveals Increased Isoform Diversity in Key Transcription Factor Effectors of Intercellular Signalling at the Invertebrate-Vertebrate Transition

Nuria P. Torres‐Aguila, Marika Salonna, Sebastian M. Shimeld…·David E. K. Ferrier

The paper uses long-read sequencing to compare isoform diversity of key transcription factors in invertebrate and vertebrate species, finding increased diversity in vertebrates.

DOI 10.1186/s12915-026-02522-w

C. eleganshuman

𝕏 PostBluesky

Developmental BiologybioRxivPreprintNov 11, 2025

WNT inhibition primes the transcriptional landscape of mesoderm to initiate a phased ventricular cardiomyocyte specification programme

Víctor Velecela, Anna K. Bassil, E Fawcett…·Stefan Hoppler

This study identifies WNT inhibition-dependent and -independent transcriptional regulators guiding human ventricular cardiomyocyte specification using single-cell RNA sequencing.

DOI 10.1101/2025.11.11.687613

humanscRNA-seq

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Developmental BiologyJournal of Cell SciencePeer-reviewedAug 22, 2025

WNT-mediating TCF/LEF transcription factor gene expression in early human pluripotency and cell lineages differs from the rodent paradigm

Connor Ross, Paula A. Balestrini, Lawrence E. Bates…·Stefan Hoppler

The paper compares WNT/{beta}-catenin signalling and TCF/LEF gene expression in human and mouse pluripotent stem cells, revealing species-specific differences in early development.

5 citations

humanmouse

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Developmental BiologyeLifePeer-reviewedJun 30, 2022

Positive Feedback Regulation of fzd7 Expression Robustly Shapes Wnt Signaling Range in Early Heart Development

Takayoshi Yamamoto, Yuta Kambayashi, Boni Anatole Afouda…·Stefan Hoppler

The paper shows that feedback regulation of fzd7 expression and sFRP1 localization via heparan sulfate restrict Wnt signaling to shape a thin pericardium during heart development.

17 citations

experimental assay

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