Connor Ross

WNT-mediating TCF/LEF transcription factor gene expression in early human pluripotency and cell lineages differs from the rodent paradigm

The paper compares WNT/{beta}-catenin signalling and TCF/LEF gene expression in human and mouse pluripotent stem cells, revealing species-specific differences in early development.

A new resource of clonal pluripotent human stem cell lines exhibiting inter- and intra-embryo consistency and variability

The paper describes a resource of clonal human pluripotent stem cell lines derived from embryos, showing intra- and inter-embryo variation and potential for modeling chromosomal mosaicism.

Plakoglobin is a mechanoresponsive regulator of naïve pluripotency

This study shows that Plakoglobin regulates naive pluripotency in mouse ESCs through mechanosensitivity, with expression specific to the blastocyst stage in human and mouse embryos.