Antonella De Lillo

The paper analyzes polygenicity differences across health domains in East Asian and European populations using genome-wide data from multiple cohorts.

This study identifies 54 risk loci for hearing loss in adults across multiple cohorts, revealing sex differences, ancestry-specific polygenic risks, and interactions with environmental factors like noise and smoking.

This study analyzes ancestry diversity changes in the Million Veteran Program over time and shows that refined ancestry modeling reduces population stratification in GWAS of height.

This paper integrates genetic transcriptomics and electronic health records to show increased hepatic Transthyretin expression is linked to specific surgical procedures and health outcomes like osteoarthritis and carpal tunnel syndrome.

The paper investigates genetic correlations between severe COVID-19 and traits like alcohol use and diabetes in over 1 million participants, showing genetic links and potential causality.

The paper investigates how evolutionary processes, including Denisovan and Neanderthal introgression, affect the genetics of complex traits in East Asians using genome-wide association data.

This study identifies epigenomic changes in African American Transthyretin Val122Ile carriers linked to heart disease and outpatient surgeries, revealing dysregulated amyloid mechanisms.

The paper identifies methylation sites associated with hereditary Transthyretin amyloidosis through an epigenome-wide association study.

The paper identifies allele frequency and regulome tagging differences between UKB and 1KG populations for GWAS loci, showing population-specific associations and potential biases.

This study identifies novel associations between TTR and RBP4 gene variants and multiple phenotypes related to hereditary and senile systemic amyloidoses in a large cohort.