Author

Shuning He

Boston Children's HospitalORCID 0000-0003-0747-2425Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Alfred Thomas LookiD· 2 shared Adam TurňaiD· 1 shared Alla Berezovskaya· 1 shared Amandeep BhamraiD· 1 shared Amélie VrommaniD· 1 shared Brian J. AbrahamiD· 1 shared Brittaney A. LeeperiD· 1 shared Carlo FisicaroiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Alfred Thomas LookORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

MYC-induced oncogenesis is dependent on acidic patches within its N-terminal intrinsically disordered domain.

Víctor Llombart, David O’Connor, Jonas Demeulemeester, Amandeep Bhamra, Silvia Šurinová, Adam Turňa, Kent T.M. Fung, Lingyi Wang, Yang Li, Tanya Rapoz-D’Silva, Farah Ahmed, Henri Niskanen, Ida Stöppelkamp, Denes Hnisz, Sandro Bottaro, , Marc R. Mansour

This study identifies acidic patches in the MYC N-terminal disordered domain essential for oncogenesis and chromatin interaction, offering new therapeutic targets.

bioRxiv · Jun 16, 2025 · PreprintCancer Biology

Multitargeted Reduction of Inflammation and Atherosclerosis in Tet2-deficient CHIP via XPO1 Inhibition and Atf3 restoration

Nicole Prutsch, Amélie Vromman, Brittaney A. Leeper, Meng‐Yu Chen, Julia H. Keating, Shuning He, Alla Berezovskaya, Siyang Ren, Mariana Janini Gomes, Eduardo J.E. Folco, Philipp J. Rauch, Prafulla C. Gokhale, Mark W. Zimmerman, Donna S Neuberg, Brian J. Abraham, , Alfred Thomas Look

bioRxiv · Jun 12, 2025 · PreprintImmunology