Genetic & Genomic MedicineThe American Journal of Human GeneticsPeer-reviewed
A novel and efficient machine learning Mendelian randomization estimator applied to predict the safety and efficacy of sclerostin inhibition
Marc‐André Legault, Jason Hartford, Benoît J. Arsenault…·Joëlle Pineau
This paper introduces a machine learning Mendelian randomization estimator, Quantile IV, to assess the causal effects of sclerostin inhibition on bone and cardiovascular outcomes using UK Biobank data.
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