Synthetic BiologyACS Synthetic BiologyPeer-reviewed
CRISPR-Cas-mediated tethering recruits the yeast HMR mating-type locus to the nuclear periphery but fails to silence gene expression
Emily R. Cliff, Robin L. Kirkpatrick, Daniel Cunningham‐Bryant…·Jesse G. Zalatan
This study shows that CRISPR-Cas-mediated tethering recruits the yeast HMR locus to the nuclear periphery but does not silence gene expression, unlike a Gal4-mediated system.
DOI 10.1021/acssynbio.1c00306