Benedikt S. Saller

This study shows that Yersinia-induced cell death and IL-1β release are driven by spatially and temporally distinct but functionally connected death complexes.

This paper identifies vacuolar disruption as a trigger for NLRP3 inflammasome activation in Toxoplasma gondii infection and shows ROP5 and ROP18 inhibit IL-1β release by protecting the parasitophorous vacuole and interacting with GBP5.