Author

Winslow Yost

University of PennsylvaniaORCID 0009-0002-8012-972XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Igor E. BrodskyiD· 3 shared Arin CoxiD· 1 shared Ashutosh B. MahaleiD· 1 shared Beatrice I. HerrmanniD· 1 shared Bohdana M. Discher· 1 shared Charles‐Antoine AssenmacheriD· 1 shared Christopher M. BourneiD· 1 shared Cornelius Y. TaabazuingiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

Igor E. BrodskyORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

MicrobiologybioRxivPreprintSep 10, 2025

Innate detection of Salmonella replication triggers caspase-8-dependent apoptosis via TLR-driven TNF signaling and NLRC4-mediated sensing of the SPI-2 Type III secretion system

Beatrice I. Herrmann, Maxime Zamba‐Campero, Reyna Garcia Sillas…·Igor E. Brodsky

The paper shows replicating Salmonella triggers TNF- and caspase-8-driven apoptosis via TLR4 and SPI-2, distinct from non-replicating Salmonella-induced pyroptosis.

1 citation

mouseexperimental assay

MicrobiologymBioPeer-reviewedSep 9, 2025

TNF signaling maintains local restriction of bacterial founder populations in intestinal and systemic sites during oral Yersinia infection

Stefan T. Peterson, Katherine G. Dailey, Karthik Hullahalli…·Igor E. Brodsky

This study shows that small bacterial founder populations independently colonize intestinal and systemic tissues during Yersinia infection, with TNF signaling restricting dissemination.

9 citationstop 3%

mousebulk RNA-seq

BiochemistrybioRxivPreprintFeb 23, 2025

Chemical Tools Based on the Tetrapeptide Sequence of IL-18 Reveals Shared Specificities between Inflammatory and Apoptotic Initiator Caspases

Christopher M. Bourne, Nicole R. Raniszewski, Madhura Kulkarni…·Cornelius Y. Taabazuing

The paper develops a new peptide-based inhibitor targeting caspase-8 and reveals shared specificities between inflammatory and apoptotic caspases.

2 citations

humanproteomics