Brooke E Ryan

This study examines phenotypic heterogeneity and environmental regulation of urovirulence in Klebsiella pneumoniae UTI isolates, finding high phenotypic variability and shared colonization ability.

This study identifies arginine as a key regulator of mucoidy in hypervirulent Klebsiella pneumoniae, showing it activates the rmpADC promoter and modulates capsular polysaccharide chain length, impacting immune evasion and in vivo fitness.