Yutaka Suzuki

This study introduces TISCA2 and IncepTIS to map and predict stress-responsive translation initiation sites, revealing tissue-specific patterns and enabling engineered mRNA 5' leaders.

This study shows that gut microbes influence germline stem cell proliferation in Drosophila by modulating metabolism, circadian genes, and hormonal signaling across tissues.

The paper identifies ALBA proteins that form stress-inducible nuclear condensates to suppress gene inducibility during osmotic stress in plants.

The paper identifies the candidate gene SUGI_0493010 for MS2-type male sterility in Japanese cedar using linkage mapping and transcriptomic data.

The paper identifies POSTN-expressing cancer-associated fibroblasts (CAFs) linked to chemoradiotherapy resistance in rectal cancer using spatial multi-omics data.

The paper identifies a gut cyanobacterial lineage, Gastranaerophilales, enriched in African populations and reduced in industrialized societies.

This study uses molecular pixelation to profile CAR protein organization dynamics in CAR-T therapy, revealing co-localization network remodeling linked to clinical outcomes.

This study generates the first spatial transcriptomic atlas of the adult Ciona neural complex, revealing molecular zonation and functional roles of key regions like the neural gland.

The paper maps lineage trajectories and gene regulatory networks of cardiopharyngeal neural crest cells in mice, identifying a Hox-Meis-regulated transition associated with cardiac cushion development.

The paper constructs a pangenome graph reference for Japanese and Saudi Arabian populations, showing improved variant detection compared to linear references and comparable performance to existing pangenome graphs.

The paper identifies a novel giant extrachromosomal element, Inocles, prevalent in the human oral microbiome that contributes to bacterial stress tolerance and may serve as a biomarker for gastrointestinal cancers.

This study identifies the BmMasc-BmPSI complex as essential for male-type Bmdsx splicing in silkworms by binding to female-specific introns and exons.

This study shows that astrocytic C3 production exacerbates neuronal mitochondrial dysfunction and necroptosis in tauopathy models, and that anserine can mitigate these effects.

The paper examines how obesity disrupts the temporally ordered metabolic network in the liver during starvation, revealing structural robustness but temporal vulnerability.

This study identifies Scarb1-mediated endothelial-fibroblast interactions as a driver of EndMT and heart failure progression, showing that targeting Scarb1 can improve cardiac function.

The paper improves the genome assembly of the Japanese honey bee using homology-based methods and nanopore long-reads, resulting in a more contiguous and complete genome.

This study uses hybrid long-read and short-read sequencing to complete the genome of Staphylococcus aureus RN4220, resolving repeats and identifying previously fragmented genes.

This study compares age-associated transcriptome changes in zebrafish and rat to identify common and species-specific aging features.

MoMI-G is a web-based genome browser for visualizing structural variants and other genomic annotations, enabling intuitive exploration of large and nested variants.

The paper develops a computational method to detect microbial contaminants in NGS data and assesses their functional impact on host molecular pathways.

The paper identifies 48 mRNAs targeted by PUM1-mediated decay and shows that DNA damage inhibits this decay to activate DNA repair.

The paper examines the temporal dynamics of histone modifications in mouse dendritic cells after LPS stimulation, revealing distinct patterns and links to transcription factor activity.

The paper constructs a trans-omic network of insulin action using phosphoproteomic, transcriptomic, and metabolomic data to identify fed and fasting insulin signals.

The paper identifies genomic regions interacting with the Pax5 promoter in chicken B cells using iChIP-Seq and in vitro enChIP-Seq, showing B cell-specific regulation and validating their utility for functional genomic analysis.