Marine Luciano

CurvoChip enables programmable curvature changes on epithelial monolayers to study mechanobiological responses, revealing curvature orientation's impact on cell and nuclear morphology.

This study shows that geometric confinement affects ERK signaling and collective migration in epithelial tissues by altering mechanical states through actomyosin contractility.

This study shows that multiscale curvature influences epithelial cell shape, nuclear organization, and tissue thickness, while maintaining nuclear geometry.

This study shows electric fields modulate keratocyte migration speed and alignment without changing turning dynamics.

This study shows migrating cells retain a mechanical memory of past morphological states through actin cortex remodeling, aiding navigation in confined spaces.

This study shows that D-chiral collagen-mimetic peptides reduce cell spreading and adhesion by destabilizing integrin interactions, highlighting the role of ECM chirality in cell migration.