Aurélien Roux

The paper shows that clathrin turnover switches during endocytosis, affecting coat size and organization in yeast.

The paper shows that ESCRT-III-mediated membrane bending directionality arises from bilayer asymmetry rather than intrinsic ESCRT properties.

This study shows HRS forms 2D condensates that drive flat clathrin lattice assembly on endosomes, with cholesterol enhancing this process.

The paper presents a standardized framework for analyzing nematic order in cellular tissues and identifies subdiffusive defect dynamics inconsistent with current active nematic theory.

This study analyzes 3D epithelial tissue packing in MDCK cells, revealing correlations between cell height, skewing, and substrate properties during proliferation.

This study shows that multiscale curvature influences epithelial cell shape, nuclear organization, and tissue thickness, while maintaining nuclear geometry.

Benchmarking fluorescence lifetime estimators for the membrane mechanosensor Flipper-TR across microscopes, laser frequencies, and photon budgets establishes practical guidelines for quantifying relative lipid packing dynamics in live cells.

This study identifies an ancient membrane fission mechanism in Asgard archaea, showing ESCRT-III's role in cell compartmentalization predates eukaryogenesis.

The paper demonstrates that adherent cells maintain spatial gradients of membrane tension through actin dynamics and membrane-cortex attachments, with tension lowest at adhesion edges and highest at protrusions.

The paper shows that TORC2 regulates sterol redistribution to recover from membrane perturbation by small amphipathic molecules in yeast and mammalian cells.

The paper identifies evolutionarily conserved principles of ESCRT-III-mediated membrane remodeling using an Asgard archaeal two-subunit system, showing homology to eukaryotic ESCRT-IIIB and IIIA.

The paper shows that topological defects in actin nematic order are necessary for head regeneration in Hydra, acting as mechanical organizers of morphogenesis.