Author

Lauri Moilanen

Central Finland Health Care DistrictORCID 0000-0003-0836-4899Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Hanna Selin· 1 shared Joris VriensiD· 1 shared Jukka‐Pekka MeckliniD· 1 shared Jussi NikkolaiD· 1 shared Juuso Vuorinen· 1 shared Kirsi PylvänäineniD· 1 shared Lauri Ryyppö· 1 shared Maarit AhtiaineniD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Hanna Selin

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2 papers

Recent·Most cited

Cancer BiologyCell ReportsPeer-reviewedOct 1, 2025

Constrained hypermutation and absence of TERT promoter mutations in Lynch syndrome-associated urothelial cancer

Jussi Nikkola, Lauri Ryyppö, Juuso Vuorinen…·Matti Annala

This study analyzes the somatic mutation landscape of Lynch syndrome-associated urothelial cancer and finds a lack of TERT promoter mutations and a distinct mutation profile.

2 citations

humanDNA methylation

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NeurosciencebioRxivPreprintApr 30, 2020

Upregulation of TRPM3 drives hyperexcitability in nociceptors innervating inflamed tissue.

Marie Mulier, Nele Van Ranst, Nikky Corthout…·Lauri Moilanen

This study shows that TRPM3 upregulation in nociceptors contributes to heat hyperalgesia during inflammation, with pharmacological inhibition reducing TRPV1 and TRPA1 responses.

1 citation

mousebulk RNA-seq

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