Jan Andreas Adelmann

The paper challenges the traditional view that morphogen concentration fluctuations determine transition zone width, showing instead that cellular readout noise is the key factor.

The paper analyzes how cell size and gradient parameters affect morphogen gradient precision, showing that smaller cell areas enhance patterning accuracy in developing tissues.

This study compares the positional error of morphogen gradients under linear and non-linear decay using simulations, finding minimal reduction in error for physiological noise levels and larger error for non-linear decay far from the source in tissues with flux barriers.