Cell BiologybioRxivPreprint
Loss of physiological stretch elicits an inflammatory, plaque-like transcriptional state in cultured human aortic smooth muscle cells
Lise Filt Jensen, Anton Markov, Laura Alonso-Herranz…·Julián Albarrán-Juárez
This study shows that physiological stretch reduces inflammation in cultured human aortic smooth muscle cells, while static culture or excessive stretch promotes an inflammatory, plaque-like state.
DOI 10.1101/2025.10.29.685276