Author

Vlad Cojocaru

Utrecht UniversityORCID 0000-0003-0886-3401Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Biophysics· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Alexandre M. J. J. BonviniD· 1 shared Anna EngeliD· 1 shared Brian Jiménez‐GarcíaiD· 1 shared Caitlin M. MacCarthyiD· 1 shared Charlotte W. van NoortiD· 1 shared Cunliang GengiD· 1 shared Francesco AmbrosettiiD· 1 shared Gal Keshet· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Alexandre M. J. J. BonvinORCID

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3 papers

Recent·Most cited

BiophysicsBiophysical JournalPeer-reviewedSep 14, 2026

Conformational plasticity and sequence specificity interplay in non-canonical tandem RRM-RNA binding

Roxana Vasarhelyi, Vlad Cojocaru

This study investigates how conformational plasticity and sequence specificity interact in tandem RRM-RNA binding using molecular dynamics simulations of DND1.

DOI 10.1016/j.bpj.2026.09.015

biophysical modelingprotein folding & dynamics

𝕏 PostBluesky

BioinformaticsProteins Structure Function and BioinformaticsPeer-reviewedDec 30, 2024

Integrative modeling in the age of machine learning: a summary of HADDOCK strategies in CAPRI rounds 47-55

Victor Reys, Marco Giulini, Vlad Cojocaru…·Alexandre M. J. J. Bonvin

The paper summarizes HADDOCK's performance in CAPRI rounds 47-55, highlighting the effectiveness of integrating HADDOCK with AI-driven methods like AlphaFold2 for protein complex structure prediction.

7 citations

humanprotein structure

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Developmental BiologyCell stem cellPeer-reviewedDec 22, 2023

Enhancing Sox/Oct cooperativity induces higher-grade developmental reset

Caitlin M. MacCarthy, Guangming Wu, Vikas Malik…·Sergiy Velychko

This study identifies a Sox2 mutation that enhances Sox/Oct cooperativity, improving iPSC reprogramming efficiency and enabling reprogramming of aged cells across species.

38 citations

humannon-human primate

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