Uri Neri

The paper analyzes CRISPR spacers from metagenomic data to reveal patterns of CRISPR targeting across Earth's biomes, identifying selection pressures and non-host phage interactions.

VHAMSTeR predicts viral host associations across five categories using genomic language models and biological features, outperforming existing methods and uncovering new RNA bacteriophages.

This paper organizes a community challenge to develop automated virus taxonomy classification tools and evaluates their performance on a combined dataset of expert-curated and metagenomic sequences.

RdRpCATCH consolidates multiple RdRp pHMM databases into a single platform for RNA virus discovery and taxonomic annotation, improving accessibility and performance.

This paper discovers a new archaeal virus that suppresses host immunity gene transcription, leading to faster growth of its host when the virus is removed.

The paper compares sequence search tools for detecting CRISPR spacer-target interactions and finds significant differences in their performance.

The paper uses protein structure prediction to analyze dark matter proteins in Orthornavirae, identifying new domains and highlighting the prevalence of disordered regions.

The paper identifies a novel icosahedral virus, FoIV1, challenging the classification of Deltaflexiviridae as capsidless and suggesting most deltaflexiviruses have icosahedral virions.

The paper expands the global RNA virome by five-fold, identifying new clades of RNA bacteriophages and revealing novel virus-host interactions.