Intracellular pH controls Wnt signaling downstream of glycolysis in the vertebrate embryo
Masayuki Oginuma, Yukiko Harima, Fengzhu Xiong, Olivier Pourquié
The paper shows that aerobic glycolysis increases intracellular pH in tail bud cells, promoting β-catenin acetylation and Wnt signaling, which drives mesodermal fate over neural fate.