Author
RIKEN Center for Biosystems Dynamics ResearchORCID 0000-0003-0948-2504Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Mingming Chen, Naoyoshi Kumakura, Hironori Saito…·Shintaro Iwasaki
The paper identifies a fungal mutation that allows survival on plants producing toxic rocaglates by altering eIF4A, a target of these compounds.
Kazuhiro Kashiwagi, Yuichi Shichino, Tatsuya Osaki…·Takuhiro Ito
This study identifies SFSV NSs as a viral protein that suppresses the integrated stress response by binding to eIF2B and preventing eIF2(P) from inhibiting nucleotide exchange.
Kazuhiro Kashiwagi, Takeshi Yokoyama, Madoka Nishimoto…·Takuhiro Ito
The paper determines cryo-EM and crystal structures of eIF2B with phosphorylated and unphosphorylated eIF2 to reveal how eIF2 phosphorylation inhibits eIF2B activity.