Author

Nina L. Fransen

Netherlands Institute for NeuroscienceORCID 0000-0003-0958-7162Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:proteomics· 1

Frequent Co-Authors

Inge HuitingaiD· 2 shared Alberto ParadelaiD· 1 shared Alberto Pérez‐SamartíniD· 1 shared Aldo BorrotoiD· 1 shared Aldo JongejaniD· 1 shared Alejandra M. Arroyo· 1 shared Alejandro Marmolejo-GarzaiD· 1 shared Aletta M.R. van den BoschiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Inge HuitingaORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintJul 2, 2026

Dynamic interplay of polygenic risk across brain disorders, neuropathological endophenotypes, and neuropsychiatric symptoms

Nienke Mekkes, Umesh Kumar, Eric Hoekstra…·Inge R. Holtman

The paper integrates genotype, clinical, and neuropathological data from 2,553 donors to show genetic risk overlaps across brain disorders and neuropsychiatric symptoms.

DOI 10.64898/2026.06.30.26356924

humanbulk RNA-seq

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NeurosciencebioRxivPreprintAug 23, 2024

TAF1-dependent transcriptional dysregulation underlies multiple sclerosis

Claudia Rodríguez-López, Ivó H. Hernández, José Terrón-Bautista…·José J. Lucas

This study identifies TAF1-dependent transcriptional dysregulation as a mechanism underlying multiple sclerosis progression and presents an in vivo model for therapeutic development.

DOI 10.1101/2024.08.23.609325

humanbulk RNA-seq

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NeuroscienceNature CommunicationsPeer-reviewedFeb 23, 2024

Profiling of microglia nodules in multiple sclerosis reveals propensity for lesion formation

Aletta M.R. van den Bosch, Marlijn van der Poel, Nina L. Fransen…·Jörg Hamann

The paper examines microglia nodules in multiple sclerosis and finds they are associated with higher lesion load and specific gene expression changes compared to stroke.

74 citationstop 1%

humanproteomics

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