Author

Andrew P. Sikkema

New England Biolabs (United States)ORCID 0000-0003-0968-1845Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Gregory J. S. LohmaniD· 2 shared Barbra D. FerrelliD· 1 shared David A. MeadiD· 1 shared Erica BickertoniD· 1 shared Ge WuiD· 1 shared Giulia DowgieriD· 1 shared Graham FreimanisiD· 1 shared James KirkiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

Gregory J. S. LohmanORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintMay 21, 2026

Single amino acid substitution in DNA Polymerase I dramatically alters infection dynamics of bacteriophage T7

Rachel A. Keown, Andrew P. Sikkema, Victoria Barbone…·Shawn W. Polson

This study shows that a single amino acid substitution in phage T7's DNA polymerase I significantly affects infection dynamics in the T7-E. coli system.

DOI 10.64898/2026.05.20.726624

bacteria (other)proteomics

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GeneticsPLoS ONEPeer-reviewedJul 25, 2024

One-pot Golden Gate Assembly of an avian infectious bronchitis virus reverse-genetics system

Katharina Bilotti, Sarah Keep, Andrew P. Sikkema…·Erica Bickerton

This paper develops a Golden Gate Assembly-based reverse genetics system for avian infectious bronchitis virus to enable rapid generation of mutants and gene replacements.

15 citations

experimental assay

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