Author

Erica Bickerton

The Pirbright InstituteORCID 0000-0002-4012-1283Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Organism:plant (other)· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Sarah KeepiD· 4 shared Basudev PaudyaliD· 2 shared Christine S. RollieriD· 2 shared Ehsan Sedaghat-RostamiiD· 2 shared Elma Z. TchilianiD· 2 shared Emily BriggsiD· 2 shared Graham FreimanisiD· 2 shared James KirkiD· 2 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersImmunology

Sarah KeepORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Infection drives localised and individualised antibody repertoires, whereas immunisation promotes repertoire convergence in pig

Emily Briggs, Shafiyeel Chowdhury, Bharti Mittal, Valentine Chaillot, Charlotte May, Kevan Hanson, Ehsan Sedaghat-Rostami, Sanis Wongborphid, Erica Bickerton, Basudev Paudyal, Christine S. Rollier, Cornelis A. M. de Haan, Kristien Van Reeth, Sarah Keep, Matthew D. J. Dicks, , Elma Z. Tchilian

This study compares antibody repertoires in pigs after infection and immunisation, finding infection drives compartmentalised, individualised responses while immunisation promotes convergent, public repertoires.

Discovery Immunology · Oct 23, 2026Peer-reviewedImmunology

Pathogenesis and immune response to respiratory coronaviruses in their natural porcine host

Ehsan Sedaghat-Rostami, Brigid Veronica Carr, Yang Liu, Sarah Keep, Fabian Z. X. Lean, Isabella Atkinson, Albert Fones, Basudev Paudyal, James Kirk, Eleni Vatzia, Simon Gubbins, Erica Bickerton, Emily Briggs, Alejandro Núñez, Adam McNee, , Elma Z. Tchilian

This study compares immune responses and pathogenesis in pigs infected with two porcine respiratory coronavirus strains, finding that a more severe strain induces stronger inflammation and immune responses linked to pneumonia.

The Journal of Immunology · Apr 30, 2025Peer-reviewedImmunology

One-pot Golden Gate Assembly of an avian infectious bronchitis virus reverse-genetics system

Katharina Bilotti, Sarah Keep, Andrew P. Sikkema, John M. Pryor, James Kirk, Katalin Földes, Nicole Doyle, Ge Wu, Graham Freimanis, Giulia Dowgier, Oluwapelumi O. Adeyemi, S. Kasra Tabatabaei, Gregory J. S. Lohman, Erica Bickerton

This paper develops a Golden Gate Assembly-based reverse genetics system for avian infectious bronchitis virus to enable rapid generation of mutants and gene replacements.

PLoS ONE · Jul 25, 2024Peer-reviewedGenetics

Comparative analysis of gene expression in virulent and attenuated strains of infectious bronchitis virus at sub-codon resolution

Adam M. Dinan, Sarah Keep, Erica Bickerton, Paul Britton, Andrew E. Firth, Ian Brierley

This study compares gene expression in virulent and attenuated IBV strains using RNASeq and RiboSeq, revealing differences in transcription, translation, and host response.

Journal of Virology · Jun 21, 2019Peer-reviewedGenomics