Graham Freimanis

This study compares the pathogenesis and immune responses of EAavH1N1 and IDV in pigs, finding distinct viral kinetics and immune activation profiles.

The paper presents a high-quality telomere-to-telomere assembly of the LSDV genome using long-read sequencing, resolving structural ambiguities and improving genomic analysis.

Cattle B3.13 H5N1 polymerase gained PB2 M631L and PA K497R, boosting replication in bovine and human cells via better bovine ANP32A use; later PB2 E627K and D740N add activity.

This study compares immune responses and pathogenesis in pigs infected with two porcine respiratory coronavirus strains, finding that a more severe strain induces stronger inflammation and immune responses linked to pneumonia.

This paper develops a Golden Gate Assembly-based reverse genetics system for avian infectious bronchitis virus to enable rapid generation of mutants and gene replacements.

This study uses single-cell RNA sequencing and flow cytometry to analyze immunological changes in pig lungs after influenza infection or vaccination, revealing lasting effects on immune cell populations and function.

The paper presents a highly contiguous genome assembly of the inbred Babraham pig, confirming homozygosity and characterizing immunogenetic variation.