Xia Gao

This study identifies a shared cellular origin for supraclavicular brown adipocytes and beige adipocytes in inguinal white adipose tissue through lineage tracing.

This study shows that combining enzalutamide with DRP-104 enhances anti-tumor immunity by reducing Treg cells and improving CD8+ T cell activity in prostate cancer.

This study shows that dietary methionine restriction enhances T cell metabolism and improves anti-PD1 checkpoint blockade efficacy in immunocompetent tumor models.

This study investigates how cancer cells adapt to purine shortage stress and identifies vulnerabilities in purine metabolism and microtubules as therapeutic targets.

This paper investigates 4-Methylumbelliferone's potential as a repurposed treatment for liver fibrosis, finding that it lacks efficacy at translatable doses and has an unclear mechanism.

The paper shows that methionine metabolism affects H3K4me3 peak width, which encodes gene expression and cell identity, despite stable peak locations.