Author

Sirkku A. Peltonen

University of TurkuORCID 0000-0003-0990-1430Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Dani FlinkmaniD· 2 shared Eleanor T. CoffeyiD· 2 shared Peter JamesiD· 2 shared Prasannakumar DeshpandeiD· 2 shared Valtteri KaasineniD· 2 shared Ye HongiD· 2 shared Elena Goltseva· 1 shared Jelena GnjatoviciD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersNeuroscience

Dani FlinkmanORCID

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2 papers

Recent·Most cited

Neurosciencenpj Parkinson s DiseasePeer-reviewedFeb 6, 2023

Regulators of proteostasis are translationally repressed in fibroblasts from sporadic and LRRK2-G2019S Parkinson's patients

Dani Flinkman, Ye Hong, Jelena Gnjatovic…·Eleanor T. Coffey

The paper identifies translational repression of proteostasis regulators in fibroblasts from both sporadic and LRRK2-G2019S Parkinson's patients using proteomics.

20 citations

humanproteomics

𝕏 PostBluesky

NeuroscienceThe FASEB JournalPeer-reviewedSep 14, 2020

Protein synthesis is suppressed in sporadic and familial Parkinson's Disease by LRRK2

Prasannakumar Deshpande, Dani Flinkman, Ye Hong…·Eleanor T. Coffey

This study shows that LRRK2 activity suppresses protein synthesis in Parkinson's disease, with inhibition restoring normal translation in patient fibroblasts.

35 citations

humanmouse

𝕏 PostBluesky