Author

Spencer L. Nystrom

University of North Carolina at Chapel HillORCID 0000-0003-1000-1579Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:Drosophila· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:software / tool· 1 Approach:statistical model· 1

Frequent Co-Authors

Daniel J. McKayiD· 3 shared Iswar K. HariharaniD· 1 shared Matthew J. NiederhuberiD· 1 shared Michael J StinchfieldiD· 1 shared Robin E. HarrisiD· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 7 mutual co-author links

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3 shared papersDevelopmental Biology

Daniel J. McKayORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintApr 23, 2021

Memes: an R interface to the MEME Suite

Spencer L. Nystrom, Daniel J. McKay

The paper introduces an R package called memes that provides a seamless interface to the MEME Suite for motif analysis, leveraging R/Bioconductor data structures and visualization tools.

DOI 10.1101/2021.04.23.441089

experimental assaysoftware / tool

𝕏 PostBluesky

Developmental BiologyDevelopmentPeer-reviewedFeb 24, 2020

The temporal transcription factor E93 controls dynamic enhancer activity and chromatin accessibility during development

Spencer L. Nystrom, Matthew J. Niederhuber, Daniel J. McKay

This study shows that the transcription factor E93 regulates enhancer activity and chromatin accessibility during Drosophila wing development, accelerating the developmental program by altering enhancer competence.

44 citations

DrosophilaChIP-seq

𝕏 PostBluesky

Developmental BiologybioRxivPreprintNov 6, 2019

Regenerative capacity in Drosophila imaginal discs is controlled by damage-responsive, maturity-silenced enhancers

Robin E. Harris, Michael J Stinchfield, Spencer L. Nystrom…·Iswar K. Hariharan

The paper identifies damage-responsive, maturity-silenced enhancers that control regenerative capacity in Drosophila imaginal discs and shows their regulation by chromatin factors.

DOI 10.1101/820605

Drosophilastatistical model

𝕏 PostBluesky