Synthetic BiologybioRxivPreprint
Oral delivery of GLP-1R agonist by an engineered probiotic yeast strain has anti-obesity effects in mice
Karl Alex Hedin, Hongbin Zhang, Vibeke Kruse…·Morten Otto Alexander Sommer
This study engineers a probiotic yeast to produce a GLP-1R agonist in the gut, reducing obesity in mice through improved metabolism and weight loss.
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