Luís Gustavo Oliveira de Sousa

This study shows that ULK1 and ULK2 regulate skeletal muscle growth by balancing protein synthesis and degradation, with lifelong deficiency causing hypertrophy but reduced muscle quality and function, while short-term deficiency allows hypertrophy without impairment.

This study investigates how UBR-box E3 ubiquitin ligases respond to changes in protein synthesis and skeletal muscle size, finding increased abundance and activity of these ligases under conditions of muscle growth and regeneration.

This study profiles multi-omic changes in multiple tissues of rats during endurance exercise training, identifying molecular adaptations and sex-specific responses across time.