Andrea Lynn Hevener

This study identifies shared and sex-specific molecular responses to endurance training in skeletal muscle using multi-omics data from rats.

The paper identifies tissue-specific transcriptional regulatory programs in rats undergoing endurance exercise training by integrating chromatin accessibility, DNA methylation, and gene expression data.

This study shows that UCP1-deficient mice adapt to cold by increasing mitochondrial calcium uptake via MCU, enhancing thermogenesis without UCP1.

The study shows that mitochondrial function and oxidative metabolism markers in female mouse skeletal muscle lack intrinsic circadian regulation, despite core-clock genes showing rhythmicity.

Correlation-based endocrine network analysis of MoTrPAC rat multi-tissue omics shows 8-week endurance training reshapes inter-organ secretory crosstalk, centering subcutaneous adipose, extracellular matrix factors, and Wnt regulators.

This study examines how endurance exercise affects liver metabolism in male and female rats over time, revealing sex-specific molecular changes and protective effects.

The paper maps liver chromatin architecture using ATAC-seq and shows sex is the main factor driving diet-induced nucleosome dynamics in mice.

This study examines how endurance exercise training affects rat subcutaneous white adipose tissue, revealing sex-specific molecular responses and differences in adiposity and metabolism.

This study maps multi-omic mitochondrial changes across 19 tissues in rats after endurance exercise training, identifying tissue-specific adaptations and disease-related hubs.

This study profiles multi-omic changes in multiple tissues of rats during endurance exercise training, identifying molecular adaptations and sex-specific responses across time.

The paper identifies a mtDNA polymorphism in MOTS-c associated with increased T2D risk in males, interacting with physical activity.