Vitor Agnew Lira

This study shows that ULK1 and ULK2 regulate skeletal muscle growth by balancing protein synthesis and degradation, with lifelong deficiency causing hypertrophy but reduced muscle quality and function, while short-term deficiency allows hypertrophy without impairment.

This study combines Tat-Beclin1 and endurance training in old male mice, showing improved physical function compared to either treatment alone.

This study investigates the role of BAT ADH5 in aging, showing that its loss accelerates BAT senescence and metabolic decline, while HSF1 activation mitigates these effects.

This study identifies early aging-related changes in muscle MERC ultrastructure and proteome, which are reversed by exercise, suggesting potential therapeutic targets for sarcopenia.

This study shows ADH5 maintains BAT metabolic homeostasis by regulating S-nitrosylation and thermogenesis under obesity and cold stress.