Joshua M. Mesfin

This study uses snRNAseq to identify cell-specific pro-repair responses induced by an infusible ECM biomaterial after myocardial infarction.

This study shows that an infusible extracellular matrix biomaterial improves survival in a mouse model of severe systemic inflammation by reducing inflammation and organ failure.

This study uses spatial and single nucleus transcriptomics to analyze the regional and cell-specific effects of ECM hydrogel treatments in myocardial infarction, revealing differences in immune modulation and cardiac development between subacute and chronic administration.